Clinical Research Details

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Descriptive Information
RCT of EBUS-guided fine needle aspiration technique for detection of mediastinal malignancy

Hassan Chami
hchami@aub.edu.lb

IM.HC.02
Ongoing

Clinical Research - Clinical Trials (phase 0, 1,2 3 & 4)  


No
Conditions and Keywords
Compare the diagnostic yield and specimen quality of EBUS-FNA performed with and without suction applied
EBUS, FNA,Suction,Lung cancer
Study Design
Diagnostic
Safety and/or Efficacy Study
Single Blind 
Single Group
Randomized
Eligibility and IRB
Both
Min: 18
Max:
Yes
No
This is a randomized study comparing the diagnostic yield and specimen quality of EBUS-FNA performed with and without suction applied in consecutive patients with suspected malignant peribronchial masses or lymph nodes. All patients will have 2 aspirations of the peribronchial lesion with suction applied and 2 aspirations without suction performed in random order. The diagnostic yield and specimen quality of the specimen obtained with the two techniques will be compared.

 Fifty consecutive patients undergoing EBUS at AUBMC for suspected malignancy will be enrolled.

 Consecutive patients with suspected malignant peribronchial masses or lymph nodes undergoing endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-FNA) will enrolled. All participants will have 4 needle aspirations of each targeted peribronchial lesion. Two needle aspitations are performed while applying suction and 2 needle aspirations will be performed without applying suction in random order. the investigators will compare the diagnostic yield and the quality of the specimens obtained using the two techniques.

 Adult undergoing EBUS at AUBMC for suspected malignancy

 Coagulopathy

The lesion cannot be sampled because of intervening tumor or blood vessels. 

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