Clinical Research Details

Descriptive Information
Perioperative Systemic vs. Inhaled Steroids in Chronic Obstructive Pulmonary Disease Patients Undergoing Non-Thoracic Surgery/ DATABASE

Hassan Chami



Conditions and Keywords
Determine the efficacy of preoperative systemic corticosteroid therapy in COPD patients following non-cardiothoracic surgery
Corticosteroids therapy,COPD,Systemic steroids,Inhaled steroids
Study Design
Eligibility and IRB

Post-operative pulmonary complications (POPC) are more common in patients with Chronic Obstructive Pulmonary Disease (COPD) compared to the general population. Systemic corticosteroids are part of the mainstay treatment of COPD Exacerbations by decreasing airway Bronchospasm and inflammation. Systemic corticosteroids are also used preoperatively to reduce the incidence of POPCs in COPD patients with little evidence to support their use. The primary objective of this restrospective study is to evaluate the efficacy of preoperative systemic versus inhaled corticosteroid treatment in COPD patients undergoing noncardiothoracic surgery for prevention of POPCs. Medical records of patients admitted for elective surgery will be surveyed retrospectively as to whether they received preoperative systemic or inhaled steroids therapy. Pulmonary function tests (PFT) results will be retrieved from the PFT lab. All other patient’s information and post-operative complications will be retrieved from the NSQIP database. Post-operative complications including pulmonary complications length of stay and mortality will be compared between patients who received systemic vs. steroids.