Clinical Research Details

Descriptive Information
Molecular-guided therapy for the treatment of patients with relapsed and refractory childhood cancers

Raya Saab
rs88@aub.edu.lb

NMTRC 009
Recruiting

Clinical Research - Clinical Trials (phase 0, 1,2 3 & 4)  

Phase 2  

No
Collaborators
  • NMTRC (Neuroblastoma and Medulloblastoma Translational Research Consortium)
Sponsors
  • NMTRC (Neuroblastoma and Medulloblastoma Translational Research Consortium)
Conditions and Keywords
Refractory solid tumors, pediatrics
genomics, personalized medicine
Study Design
Treatment
Safety and/or Efficacy Study
Prospective
Open Label
Single Group
N/A: Single arm study
N/A: Not Applicable
Eligibility and IRB
Both
Min: 0
Max: 18
Yes
No

The primary objective of this study is to determine feasibility of using tumor samples to assess genomic mRNA expression arrays and DNA Mutation Panels using predictive modeling to make real-time treatment decisions for children with relapsed/refractory cancers. Secondary objectives include assessment of response, and evaluation of safety of the decision-making process, exploring the relationship between tumor genotype/phenotype and response.


Pediatric Oncology patients with resistant solid tumors