Central Line Associated Blood Stream Infection (CLABSI)
Lock therapy, Salvage of the line
Safety and/or Efficacy Study
Eligibility and IRB
1. Age>18 years, 2. CVC in place at least 14 days. In neutropenic 2 hours differential time to positivity between central and perpheral, 3. Female non-lactating and at no risk for pregnancy, 4. For short term catheters, enroll if CVC cannot be removed.
1. allergic to tetracyclin or EDTA, 2. On disulfiram drugs, 3. Severe sepsis, hemodynamic instability, 4. Prosthetic valve, 5. Signs of deep seated infection, 6. cathter exit site infection, 7. Candida line infection, 8. Previously entered on the study.