This is a prospective
comparative randomized controlled trial investigating the effect of dual
trigger on final oocyte maturation compared to the standard hCG trigger in poor
ovarian responder’s women undergoing assisted reproductive technology.
The study will be
conducted at the American University of Beirut Medical Center (AUBMC) on 126
women seeking IVF/ICSI fertility treatment.
Purposing sampling.
ü
Age: 18-44 years at the time of interview.
ü
Normal uterine cavity (as assessed by
hysteroscopy or HSG).
ü
Normal hormonal investigation: TSH, PRL.
ü
Low ovarian reserve patients (AMH<1.5ng/ml, AFC of 7 or less, 5
oocytes or less retrieved in a previous cycle)
ü
Abnormal uterine cavity (Hysteroscopy or HSG)
ü
Evidence
of untreated endocrine disorders (abnormal TSH, prolactin, testosterone and
androstenedione concentrations)