Details - Clinical Research

Clinical Research Details

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Descriptive Information

Title

Bloodstream infections and patterns of resistance in febrile patients with hematological malignancies.

Investigator Name

Souha Kanj Shararah

sk11@aub.edu.lb

Protocol Id

BIO-2018-0050

Status

Ongoing

Study Type

Observational A clinical study in which participants identified as belonging to study groups are assessed for biomedical or health outcomes. Participants may receive diagnostic, therapeutic, or other types of interventions, but the investigator does not assign participants to specific interventions (as in an interventional study).

Phase

Looking for Med Students Volunteers

Coordinators

Jeff Jabbour

jj24@aub.edu.lb

Conditions and Keywords

Conditions

Bloodstream infections and patterns of resistance in febrile patients with hematological malignancies

Keywords

BSI,bloodstream infections,febrile neutropenia

Study Design

Primary Purpose

Other: Describe in Detailed Description
Observational and epidemiological

Classification

N/A: Not Applicable

Time Perspective

Retrospective

Masking

N/A: Not Applicable

Intervention Model

N/A: Not Applicable

Allocation

N/A: Not Applicable

Observational Study Model

Cohort

Eligibility and IRB

Gender

Both

Age Limits

Min:

Max:

IRB Approval

Yes

Healthy Volunteer

Study Description

The recently published data on the epidemiology of Gram negative resistance in Lebanon did not differentiate between oncology and non-oncology patients. Moreover, the latest studies in Lebanon looking at bacteremia in patients with hematological malignancies were published around a decade ago. Recent data on the epidemiology and resistance patterns of bacteria causing blood stream infections (BSIs) in hematologic malignancy in Lebanon are lacking.

Objectives:
1- To study the epidemiology of blood stream infections in patients with hematological malignancies
2- To study the pattern of antibiotic resistance in this patient population

Population Description

Adult patients with febrile neutropenia and a documented bacteremia.

Sampling Method

Information is collected from medical charts and medical records, radiology reports and microbiology reports. Data will be entered on an electronic clinical report form.

Inclusion Criteria

Patients aged above 18 years old
Patients with hematologic malignancies, aplastic anemia, and/or those undergoing stem cell transplantation
Patient with a documented positive blood culture from one or more puncture sites.

Exclusion Criteria

Patients treated empirically with no documented positive blood cultures

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