Clinical Research Details

Descriptive Information
The effect of stapedectomy on voice

Marc Bassim



Conditions and Keywords
stapedectomy ,acoustic analysis
Study Design
N/A: Not Applicable
N/A: Not Applicable
N/A: Not Applicable
Eligibility and IRB
Min: 18
In Progress

This is a prospective cohort study. A total of 30 consecutive subjects diagnosed with otosclerosis and presenting to the otology clinic of Dr. George Zaytoun and Dr. Marc Bassim at the American University of Beirut – Medical Center will be invited to participate in this study. Dr. Maher Kasty will ask his patients, who are diagnosed with otosclerosis, at Rafik Hariri Hospital to come to the otology clinic at AUBMC and participate in the study. While the sample size might seem small, this study is the first of its kind and is intended to be a pilot study. 

A total of 20 consecutive subjects diagnosed with otosclerosis will be invited to participate in this study.

While being examined in the pre-admission unit, patients will be offered enrollment in the study where they will undergo an acoustic voice analysis through the OperaVox® application for mobile operating systems. OperaVOX is a validated iOS application that provides objective analysis of voice quality using acoustic parameters (Mat Baki et al., 2015). It also offers user-friendly interface, and novel acoustic voice analysis algorithms (Hughes et al., 2012). The tested parameters are: Habitual pitch, fundamental frequency, Voice Turbulence Index, Noise-to-Harmonic Ratio, shimmer, jitter and formant frequencies. They will then be offered another acoustic analysis simultaneously with their follow-up postoperative audiogram after 1 month using the same method.

-          Subjects above 18 years of age diagnosed with otosclerosis presenting o the otology clinic at AUBMC

-          Subjects with recent history of upper respiratory tract infection

-          Subjects with recent history of laryngeal manipulation

-          Subjects with known laryngeal pathology

-          Subjects with history of chronic ear infections

-          Subjects with previous ear surgery