Clinical Research Details

Descriptive Information
Periodontal disease and in-vitro fertilization (IVF) outcomes: A cross-sectional study

Ghina Ghazeeri



Phase 0  

  • Johnny Awwad
  • Anwar Nassar
  • Joseph Ghafari
  • Mohammad N. Itani
  • Nada Afeiche
  • Nancy Abdo
  • Fatin Khalifeh
Christine Beyrouthy
Extension: 5618
Conditions and Keywords
Periodontal disease,infertility
in vitro fertilization ,dental status,periodontal disease
Study Design
Health Services Research
N/A: Not Applicable
N/A: Not Applicable
N/A: Not Applicable
N/A: Not Applicable
N/A: Not Applicable
Eligibility and IRB
Min: 18
Max: 38

This is a prospective cross-sectional study. The main objective of this study is to assess whether poor dental status does play a role as a contributing factor to IVF failure (whether at the level of embryo quality or at the level of implantation) among patients who are trying to conceive.

patients undergoing their first cycle of in vitro fertilization (IVF) at the Assisted Reproductive Technology (ART) Unit at the American University of Beirut-Medical Center in Beirut, Lebanon. 

purposive sampling

Have a normal uterine cavity (as assessed by hysteroscopy or HSG)

Absence of hormonal, coagulation or immunological disorders

 Had healthy, fresh sperm used for their IVF procedure

 Have at least 20 natural teeth

 Do not have maternal cardiac disease that would warrant the need for antibiotics for periodontal examination or treatment


-                    Endometriosis

-                  History of an inflammatory disease and/or chronic infectious diseases

  Inherited/congenital or acquired thrombophilia and women with medical conditions requiring anti-coagulant treatment.

  An already identified medical reason for the failure of implantation.

  Extreme male factor infertility