This is a prospective observational study conducted at the American University of Beirut Medical Center aiming at:

1. Determining the risk factors of nosocomial clostridium difficile infection (CDI) (primary objective)

2. Determining the ribotype of Clostridium Difficile responsible for nosocomial and relapsing CDI in the American University of Beirut Medical Center (primary ojbective)

3. Determining the relapse rate of CDI within 8 weeks of hospital discharge defined as either repeat hospitalization or outpatient CDI relapse documentation by repeat stool testing (secondary objective)

200 prospective patients will be consecutively recruited following diagnosis of Clostridium Difficile by Toxin A/B or PCR.

Following diagnosis of Clostridium Difficile, patients will be consented to enroll in the study and their medical records checked for relevant study information. Stool samples will also undergo Clostridium Difficile ribotyping. Patients will be enrolled consecutively until 200 samples are reached.